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KMID : 0363820010350020004
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Korean Journal of Nuclear Medicine
2001 Volume.35 No. 2 p.4 ~ p.10
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Radiation Dosimetry for Radionuclide Therapy
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김은희/Eun Hee Kim
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Abstract
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The radionuclide therapy id a protocol for tumor control by administering radionuclides as the cytotoxic agents. Radionuclides concentrated at the site of cancerous lesion are expected to kill the cancerous cells with minimal injury to the
normal
tissue. The efficacy of every radionuclide treatment can be evaluated by examining the toxicity to the lesion differentiated from that to the normal tissue. Radiation dosimetry is the procedure of quantitating the energy absorbed by target
volumes
of
interest. Dosimetric information plays an indicator of the expected radiation damage and thus the therapeutic efficacy. This paper summarizes the dosimetric aspects in redionuclide therapy in terms of radionuclides of use, radiation dosimetry
methodology and considerations for each treatment in practical use.
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KEYWORD
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